Marbobroad 16%

Composition:

Each 1 ml contains Marbofloxacin                                       160 mg. Properties:

Marbofloxacin is a synthetic bactericidal antimicrobial belonging to fluoroquinolones group which acts by inhibition of DNA gyrase.

(is an essential bacterial enzyme important for bacterial DNA transitions)

Fluoroquinolones are associated with a post –antibiotic effect in number of bacteria principally gram- negative (eg. Escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa).

The fluoroquinolones are active against wide range of gram-negative and a number of gram positive anaerobes. They are highly effective against all intestinal bacterial pathogens .

Quinolone also have significant efficacy against Mycoplasma (lack of cell wall so resist antibiotics works by damaging bacterial cell wall) and chlamydia spp obligate anaerobes tend to be resist against quinolones as are most enterococcal group D streptococcal spp (S faecalis and S faecium ).

Indication:

⯈ in non-responsive cases In cattle with:

-Therapeutic treatment of respiratory infections caused by sensitive strains of Pasteurella multocida and Mannheimia haemolytica

In lactating caws

-Treatment of acute mastitis caused by sensitive strains of Escherichia coli.

-  diarrhea

Target species:

Cattle.

Dose & administration:

Rout of administration by I.M injection. For whole of product:

5 ml of the product /80 Kg b.wt *(single dose).* Withdrawal time:

-  Meat and offal 5 days.

-  Milk                   48 hours